Irinotecan 40

Irinotecan 40 mg Injection
Irinotecan 40 mg Injection is a camptothecin-derived antineoplastic agent used extensively in the treatment of colorectal and other solid tumors. It works by inhibiting DNA replication in cancer cells, thereby preventing tumor growth and progression. Irinotecan is commonly used alone or in combination chemotherapy regimens.
Product Details
Generic Name: Irinotecan (as Irinotecan Hydrochloride)
Strength: 40 mg
Dosage Form: Injection (Sterile solution for intravenous use)
Route of Administration: Intravenous (IV infusion)
Therapeutic Class: Antineoplastic Agent (Topoisomerase I Inhibitor)
Indications
Irinotecan 40 mg Injection is indicated for the treatment of:
Colorectal cancer
Gastric cancer
Lung cancer
Ovarian cancer
Pancreatic cancer
Other solid tumors as prescribed by an oncologist
Mechanism of Action
Irinotecan inhibits topoisomerase I, an enzyme required for DNA replication. This leads to DNA strand breaks and prevents cancer cell division.
Key Benefits
Proven efficacy in colorectal and gastrointestinal cancers
Widely used in combination chemotherapy regimens
Well-established safety and efficacy profile
Suitable for global oncology treatment protocols
Dosage & Administration
Dosage is individualized based on body surface area (BSA), disease condition, and patient response. Irinotecan should be administered only under strict medical supervision by qualified healthcare professionals.
Storage Conditions
Store below 25°C
Protect from light
Do not freeze
Precautions
For hospital and oncology clinic use only
Regular monitoring of blood counts and liver function is recommended
Use with caution in patients with hepatic impairment