Irinotecan 100

Irinotecan 100 mg Injection
Irinotecan 100 mg Injection is a camptothecin-derived antineoplastic agent widely used in the treatment of colorectal and other solid tumors. It acts by inhibiting DNA replication in rapidly dividing cancer cells, thereby slowing tumor growth and progression. Irinotecan is commonly administered as part of combination chemotherapy regimens.
Product Details
Generic Name: Irinotecan (as Irinotecan Hydrochloride)
Strength: 100 mg
Dosage Form: Injection (Sterile solution for intravenous use)
Route of Administration: Intravenous (IV infusion)
Therapeutic Class: Antineoplastic Agent (Topoisomerase I Inhibitor)
Indications
Irinotecan 100 mg Injection is indicated for the treatment of:
Colorectal cancer
Gastric cancer
Lung cancer
Ovarian cancer
Pancreatic cancer
Other solid tumors as prescribed by an oncologist
Mechanism of Action
Irinotecan inhibits topoisomerase I, an enzyme essential for DNA replication. This results in DNA strand breaks, preventing cancer cell division and leading to cell death.
Key Benefits
Proven efficacy in colorectal and gastrointestinal cancers
Widely used in combination chemotherapy protocols
Well-established safety and efficacy profile
Suitable for standard and global oncology treatment guidelines
Dosage & Administration
Dosage is individualized based on body surface area (BSA), disease condition, and patient response. Administration should be performed only under the supervision of qualified healthcare professionals.
Storage Conditions
Store below 25°C
Protect from light
Do not freeze
Precautions
For hospital and oncology clinic use only
Regular monitoring of blood counts and liver function is recommended
Use with caution in patients with hepatic impairment